Neural Pathfinding on Uni- and Multidirectional Photopolymerized Micropatterns
نویسندگان
چکیده
منابع مشابه
Neural Pathfinding on Uni- and Multidirectional Photopolymerized Micropatterns
Overcoming signal resolution barriers of neural prostheses, such as the commercially available cochlear impant (CI) or the developing retinal implant, will likely require spatial control of regenerative neural elements. To rationally design materials that direct nerve growth, it is first necessary to determine pathfinding behavior of de novo neurite growth from prosthesis-relevant cells such as...
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The ability to direct neurite growth into a close proximity of stimulating elements of a neural prosthesis, such as a retinal or cochlear implant (CI), may enhance device performance and overcome current spatial signal resolution barriers. In this work, spiral ganglion neurons (SGNs), which are the target neurons to be stimulated by CIs, were cultured on photopolymerized micropatterns with vari...
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ژورنال
عنوان ژورنال: ACS Applied Materials & Interfaces
سال: 2014
ISSN: 1944-8244,1944-8252
DOI: 10.1021/am501622a